Author’s response to reviews Title: ARLTS1 polymorphism is associated with an increased risk of familial cancer: evidence from a meta-analysis Authors:

Thank you for your letter 11 Apr 2017 regarding our manuscript entitled “ARLTS1 polymorphism is associated with risk of familial cancer: evidence from a meta-analysis” (HCCPD-16-00036R1). Sorry for replying your letter so late. We carefully considered the reviewer’s comments and suggestions and amended the manuscript accordingly. In addition, we have put serious efforts into revising the manuscript and made numerous editorial changes, including re-wording some sentences and correcting various spelling and grammar errors. We hope that the revised version is suitable for publication in your journal. Thanks again for your reconsideration.